Leflunomide Impurity H
Acetamide,2-cyano-N-[4-(trifluoromethyl)phenyl]-
CAS: 24522-30-3
Molecular Formula: C10H7F3N2O
Leflunomide Impurity H - Names and Identifiers
Leflunomide Impurity H - Physico-chemical Properties
| Molecular Formula | C10H7F3N2O |
| Molar Mass | 228.18 |
| Density | 1.375±0.06 g/cm3(Predicted) |
| Melting Point | 145-147℃ |
| Boling Point | 386.3±42.0 °C(Predicted) |
| pKa | 4.63±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
Leflunomide Impurity H - Upstream Downstream Industry
| Raw Materials | 1-CYANOACETYL-3,5-DIMETHYLPYRAZOLE Acetyl chloride, cyano- Ethyl cyanoacetate Cyanoacetic acid 4-Aminobenzotrifluoride |
Leflunomide Impurity H - Introduction
Acetamide,2-cyano-N-[4-(trifluoromethyl)phenyl]-is an organic compound with the chemical formula C10H8F3N3O.
Nature:
-Appearance: It is usually a white crystal or a powdery solid.
-Melting point: Its melting point is approximately between 95 and 98 ° C.
-Solubility: Its solubility in water is relatively low, but it can be well dissolved in organic solvents.
Use:
-Pesticide intermediate: It is a pesticide intermediate that can be used to synthesize pesticides and herbicides.
-Drug synthesis: It can also be used to synthesize drugs, such as antiepileptic drugs and antipsychotic drugs.
Method:
Acetamide,2-cyano-N-[4-(trifluoromethyl)phenyl]-can be prepared:
-First, tetrafluoromethylbenzene chloride (C6H4ClF3) is reacted with sodium cyanide (NaCN) to obtain cyanotetrafluoromethylbenzene (C6H4CNF3).
-Then, cyanotetrafluoromethylbenzene is reacted with Acetamide (C2H5NO) to obtain Acetamide,2-cyano-N-[4-(trifluoromethyl)phenyl]-.
Safety Information:
The compound may have certain toxicity, so appropriate safety measures should be taken when handling, such as wearing gloves and respiratory protection equipment. Avoid contact with oxidizing agents and strong acids during use or storage. Also, avoid inhalation, ingestion or contact with skin and eyes. All equipment and tools used shall be thoroughly cleaned after treatment. In the event of an accident, seek medical attention immediately and provide a safety data sheet for this compound.
Nature:
-Appearance: It is usually a white crystal or a powdery solid.
-Melting point: Its melting point is approximately between 95 and 98 ° C.
-Solubility: Its solubility in water is relatively low, but it can be well dissolved in organic solvents.
Use:
-Pesticide intermediate: It is a pesticide intermediate that can be used to synthesize pesticides and herbicides.
-Drug synthesis: It can also be used to synthesize drugs, such as antiepileptic drugs and antipsychotic drugs.
Method:
Acetamide,2-cyano-N-[4-(trifluoromethyl)phenyl]-can be prepared:
-First, tetrafluoromethylbenzene chloride (C6H4ClF3) is reacted with sodium cyanide (NaCN) to obtain cyanotetrafluoromethylbenzene (C6H4CNF3).
-Then, cyanotetrafluoromethylbenzene is reacted with Acetamide (C2H5NO) to obtain Acetamide,2-cyano-N-[4-(trifluoromethyl)phenyl]-.
Safety Information:
The compound may have certain toxicity, so appropriate safety measures should be taken when handling, such as wearing gloves and respiratory protection equipment. Avoid contact with oxidizing agents and strong acids during use or storage. Also, avoid inhalation, ingestion or contact with skin and eyes. All equipment and tools used shall be thoroughly cleaned after treatment. In the event of an accident, seek medical attention immediately and provide a safety data sheet for this compound.
Last Update：2024-04-09 21:11:58
Supplier List
Spot supply
Product Name: Leflunomide Impurity Request for quotationCAS: 24522-30-3
Tel: 0712-8899838
Email: jy6101@rmastandards.com
Mobile: 86-15787876101
QQ: 2518299249
Wechat: 15787876101
Spot supply
Product Name: 2-Cyano-N-(4-(trifluoromethyl)phenyl)acetamide Request for quotationCAS: 24522-30-3
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide Visit Supplier Webpage Request for quotationCAS: 24522-30-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 2-Cyano-N-(4-(trifluoromethyl)phenyl)acetamide Visit Supplier Webpage Request for quotationCAS: 24522-30-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide (Standard) Visit Supplier Webpage Request for quotationCAS: 24522-30-3
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Product Name: 2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide Visit Supplier Webpage Request for quotation
CAS: 24522-30-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 24522-30-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: Leflunomide Impurity Request for quotationCAS: 24522-30-3
Tel: 0712-8899838
Email: jy6101@rmastandards.com
Mobile: 86-15787876101
QQ: 2518299249
Wechat: 15787876101
Spot supply
Product Name: 2-Cyano-N-(4-(trifluoromethyl)phenyl)acetamide Request for quotationCAS: 24522-30-3
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide Visit Supplier Webpage Request for quotationCAS: 24522-30-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 2-Cyano-N-(4-(trifluoromethyl)phenyl)acetamide Visit Supplier Webpage Request for quotationCAS: 24522-30-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide (Standard) Visit Supplier Webpage Request for quotationCAS: 24522-30-3
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Product Name: 2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide Visit Supplier Webpage Request for quotation
CAS: 24522-30-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 24522-30-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
Leflunomide Impurity H
CID 16020046
5-BROMOVALERYL CHLORIDE
Violet BS
DISTEARYLDIMETHYLAMMONIUM CHLORIDE 75 % IN 2-PROPANOL/WATER
Sulfinyl chloride
Corynoline acetate
CID 16020046
5-BROMOVALERYL CHLORIDE
Violet BS
DISTEARYLDIMETHYLAMMONIUM CHLORIDE 75 % IN 2-PROPANOL/WATER
Sulfinyl chloride
Corynoline acetate
Raw Materials for Leflunomide Impurity H
1-CYANOACETYL-3,5-DIMETHYLPYRAZOLE
Acetyl chloride, cyano-
Ethyl cyanoacetate
Cyanoacetic acid
4-Aminobenzotrifluoride
Acetyl chloride, cyano-
Ethyl cyanoacetate
Cyanoacetic acid
4-Aminobenzotrifluoride